Albert Jeltsch Selected Research

Proteins (Proteins, Gene)

3/2024	Approaching the catalytic mechanism of protein lysine methyltransferases by biochemical and simulation techniques.
10/2023	Methylation of the transcription factor E2F1 by SETD6 regulates SETD6 expression via a positive feedback mechanism.
1/2023	The T1150A cancer mutant of the protein lysine dimethyltransferase NSD2 can introduce H3K36 trimethylation.
1/2020	Analysis of the Substrate Specificity of the SMYD2 Protein Lysine Methyltransferase and Discovery of Novel Non-Histone Substrates.
1/2018	The Legionella pneumophila Methyltransferase RomA Methylates Also Non-histone Proteins during Infection.
5/2015	Somatic cancer mutations in the DNMT2 tRNA methyltransferase alter its catalytic properties.
1/2015	Somatic cancer mutations in the MLL3-SET domain alter the catalytic properties of the enzyme.
12/2014	Role of somatic cancer mutations in human protein lysine methyltransferases.
5/2006	Mutations in DNA methyltransferase DNMT3B in ICF syndrome affect its regulation by DNMT3L.

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Albert Jeltsch Research Topics

Disease

25	Neoplasms (Cancer) 03/2024 - 11/2004
3	Genomic Instability 11/2012 - 03/2008
2	Infections 01/2018 - 10/2003
2	Leukemia 01/2017 - 03/2014
2	Carcinogenesis 12/2014 - 07/2008
2	variable Immunodeficiency syndrome 05/2006 - 06/2004
1	Nervous System Diseases (Neurological Disorders) 03/2024
1	Cardiovascular Diseases (Cardiovascular Disease) 03/2024
1	Prostatic Neoplasms (Prostate Cancer) 02/2024
1	Beckwith-Wiedemann Syndrome (Exomphalos Macroglossia Gigantism Syndrome) 01/2024
1	Imprinting Disorders 01/2024
1	Silver-Russell Syndrome 01/2024
1	Pathologic Processes 10/2023
1	Autism Spectrum Disorder 12/2021
1	Giant Cell Tumor of Bone 10/2020
1	Paraganglioma (Paragangliomas) 12/2019
1	Virus Diseases (Viral Diseases) 01/2018
1	Cognitive Dysfunction 12/2017
1	Mental Disorders (Mental Disorder) 01/2017
1	Genetic Translocation (Chromosomal Translocation) 12/2014
1	Ovarian Neoplasms (Ovarian Cancer) 01/2014
1	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 12/2012
1	alpha-Thalassemia 06/2011
1	X-Linked Mental Retardation (Mental Retardation, X Linked) 06/2011
1	Conversion Disorder (Astasia Abasia) 01/2009
1	Carcinoma (Carcinomatosis) 07/2008
1	Decompression Sickness (Bends) 12/2007

Drug/Important Bio-Agent (IBA)

17	DNA (Deoxyribonucleic Acid)IBA 01/2024 - 11/2004
13	MethyltransferasesIBA 05/2023 - 11/2004
10	EnzymesIBA 02/2024 - 11/2004
9	Proteins (Proteins, Gene)FDA Link 03/2024 - 05/2006
7	Histones (Histone)IBA 12/2021 - 11/2012
5	Histone-Lysine N-MethyltransferaseIBA 10/2023 - 11/2012
5	Lysine (L-Lysine)FDA Link 01/2023 - 11/2012
2	ChromatinIBA 12/2017 - 06/2004
2	Epithelial Cell Adhesion MoleculeIBA 01/2014 - 07/2008
2	hydrogen sulfite (bisulfite)IBA 01/2009 - 07/2008
1	Cadherins (E-Cadherin)IBA 03/2024
1	NucleotidesIBA 11/2023
1	TNF-Related Apoptosis-Inducing Ligand ReceptorsIBA 01/2020
1	LigandsIBA 01/2020
1	RNA (Ribonucleic Acid)IBA 01/2018
1	Cocaine (Cocaine HCl)IBA 12/2017
1	Histone MethyltransferasesIBA 01/2017
1	Asp Transfer RNAIBA 05/2015
1	Transfer RNA (tRNA)IBA 05/2015
1	tRNA MethyltransferasesIBA 05/2015
1	SGI-1027IBA 03/2014
1	Decitabine FDA Link 12/2012
1	Azacitidine (5 Azacytidine)FDA Link 12/2012
1	CytosineIBA 08/2011
1	X-linked Nuclear ProteinIBA 06/2011
1	TeaIBA 04/2011
1	PolyphenolsIBA 04/2011
1	Coffee FDA Link 04/2011
1	Small Interfering RNA (siRNA)IBA 07/2008
1	DNA modification methylase SssI (M.SssI)IBA 07/2008
1	CytidineIBA 11/2004
1	Satellite DNA (Satellite DNAs)IBA 06/2004
1	HeterochromatinIBA 06/2004
1	DNA Restriction-Modification Enzymes (Restriction Modification Systems)IBA 10/2003

Therapy/Procedure

6	Therapeutics 01/2020 - 11/2004